Production of bioactive ginsenoside Rg3(S) and compound K using recombinant Lactococcus lactis

Expression of bioactive porcine interferon-gamma by recombinant Lactococcus lactis.

Lactococcus lactis is an immunomodulator and candidate live mucosal delivery vehicle for vaccine antigens and for biologically active molecules, including immunoregulatory cytokines such as interferon-gamma (IFN-gamma). To provide a tool for investigating downregulation of allergic predisposition of pigs to experimental food allergy, porcine IFN-gamma was cloned and expressed as a fusion protei...

Lactococcus Lactis: Production and secretion of recombinant protein

Lactococcus lactis, a model lactic acid bacterium that is widely used in the dairy industry, which proves beneficial due to its easy protein secretion and purification. It is also a potential host for the production of therapeutic recombinant proteins. Many heterologous proteins have been produced in L.lactis but very few report the whole system of the gene expression machinery and its applicat...

Production of functionalized biopolyester granules by recombinant Lactococcus lactis.

Many bacteria are naturally capable of accumulating biopolyesters composed of 3-hydroxy fatty acids as intracellular inclusions, which serve as storage granules. Recently, these inclusions have been considered as nano-/microbeads with surface-attached proteins, which can be engineered to display various protein-based functions that are suitable for biotechnological and biomedical applications. ...

Folate Production by Lactococcus lactis

Production of Recombinant Peanut Allergen Ara h 2 using Lactococcus lactis

BACKGROUND Natural allergen sources can supply large quantities of authentic allergen mixtures for use as immunotherapeutics. However, such extracts are complex, difficult to define, vary from batch to batch, which may lead to unpredictable efficacy and/or unacceptable levels of side effects. The use of recombinant expression systems for allergen production can alleviate some of these issues. S...